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Tag Archives: naloxone
The opiate overdose antidote Narcan will soon be available in all CVS pharmacies in Rhode Island without a prescription. The move comes as the state is seeing a surge in recent deaths due to opiate drug overdoses, which can be reversed by Narcan, also known as naloxone. Narcan can be administered as a nasal spray or an injection, and CVS says it will offer both, following in the footsteps of a similar move by Walgreens last year.
Rhode Island ranks among the highest in the country in illicit drug use, including the non-medical use of prescription painkillers and per capita overdose deaths.
In the first four months of 2014, 90 Rhode Islanders died from accidental drug overdoses, a 23% increase from the 73 drug overdoses reported during the same period last year.
U.S. Attorney General Eric Holder is urging federal law enforcement agencies to identify, train and equip personnel who may interact with a victim of a heroin overdose with the drug naloxone. The potentially life-saving drug — which effectively restores breathing to a victim in the midst of a heroin or opioid overdose — is already carried by officers in some state and local law enforcement groups while on patrol.
The U.S. Department of Justice wants federal law enforcement agencies, as well as their state and local partners, to review their policies and procedures to determine whether personnel should be equipped and trained to recognize and respond to opioid overdose by various methods, including the use of naloxone, otherwise known as Narcan. Seventeen states and the District of Columbia have amended their laws to increase access to naloxone, resulting in over 10,000 overdose reversals since 2001.
According to Holder:
The shocking increase in overdose deaths illustrates that addiction to heroin and other opioids, including some prescription painkillers, represents nothing less than a public health crisis. I am confident that expanding the availability of naloxone has the potential to save the lives, families and futures of countless people across the nation.
New Jersey Gov. Chris Christie is urging physicians to be more careful about their prescribing habits when it comes to potentially addictive painkillers, and is encouraging their participation in the state’s voluntary drug monitoring program. The comments came at a doctors’ conference where the governor described how deeply affected he has been by the recent death of a close friend due to pain medication, according to this article.
Only about 20 to 25 percent of doctors in the state voluntarily use the program, the article says. Meanwhile, treatment centers in the state reported 7,238 admissions for painkiller addictions in 2010, 12 times more than in 2000, the article adds, citing data from the Substance Abuse and Mental Health Services Administration.
Christie had previously come under fire for rejecting an early version of the state’s Good Samaritan bill, which he claimed was too narrowly focused on encouraging more reporting of drug overdoses, rather than other aspects such as drug abuse deterrence, violence prevention and public safety. In May 2013, he signed an updated version of the bill into law, but partially vetoed a separate bill that would make the overdose antidote naloxone available to spouses, parents and guardians of people addicted to opioids. This March, the Christie administration issued a waiver allowing emergency medical technicians to administer naloxone after completing a training course.
The U.S. Food and Drug Administration has approved a prescription treatment that can be used by family members or caregivers to treat a person known or suspected to have had an opioid overdose. The hand-held device, known as Evzio, rapidly delivers a single dose of the drug naloxone and can be carried in a pocket or stored in a medicine cabinet, according to the agency. Naloxone is a medication that rapidly reverses the effects of opioid overdose and is the standard treatment for such situations, but until now it has been available mostly in hospitals and other medical settings.
Evzio is injected into the muscle (intramuscular) or under the skin (subcutaneous), the FDA said. Once turned on, the device provides verbal instruction to the user describing how to deliver the medication.
Drug overdose deaths, driven largely by prescription drug overdose deaths, are now the leading cause of injury death in the United States – surpassing motor vehicle crashes. In 2013, the U.S. Centers for Disease Control and Prevention reported the number of drug overdose deaths had steadily increased for more than a decade.
Massachusetts Governor Deval Patrick has declared a public health emergency in response to the state’s growing opioid addiction epidemic, issuing an order banning the controversial new form of hydrocodone, Zohydro, and taking a number of other steps to curb overdoses and help the addicted. In a press release, the governor said the use of oxycodone and other narcotic painkillers, often as a route to heroin addiction, has been on the rise for the last few years in Massachusetts; at least 140 people have died from suspected heroin overdoses in communities across the state in the last several months, levels previously unseen. From 2000 to 2012, the number of unintentional opiate overdoses increased by 90 percent, he added. The prescribing and dispensing of Zohydro, which was recently approved for sale by the FDA despite widespread protests, will be prohibited “until it is determined that adequate measures are in place to safeguard against the potential for diversion, overdose and misuse,” he said. The governor added:
The introduction of this new painkiller into the market poses a significant risk to individuals already addicted to opiates and to the public at large.
Rhode Island authorities are taking emergency steps to address an overdose crisis by making the overdose antidote naloxone more widely available, including to law enforcement agencies. According to this article, the state’s health department says Rhode Island is in the midst of “a severe prescription and street-drug overdose crisis” and that expanded access to naloxone — otherwise known as Narcan — has become “immediately necessary to save lives.”
The emergency regulations allow for naloxone to be prescribed not only to a person experiencing an overdose or at risk of one, but to family members and friends in a position to assist, while police departments would also be able to obtain and administer Narcan under a standing order from a prescriber, according to the article.
Rhode Island reported 55 accidental overdose deaths this year through March 4, about twice the normal number, the article says.
Fifteen states and Washington, D.C. currently have some type of Narcan distribution program, including some where family and friends of addicts receive kits in case of emergency.
Although federal data suggests that heroin use has roughly doubled across the country in recent years, the overdose antidote naloxone remains widely unavailable to many users and emergency responders — despite a success rate that normally exceeds 80% or 90%, according to this report by the Los Angeles Times.
Legislatures in Democrat and Republican states alike are considering proposals that would expand access to naloxone, otherwise known as Narcan, and 17 states plus the District of Columbia have already adopted laws expanding access to the drug, the LA Times says. Fourteen states and the District of Columbia also have passed so-called “Good Samaritan” laws that offer immunity to those who call 911 during an overdose, according to the paper.
Naloxone has few if any side effects, and is virtually 100% effective when used on an overdose victim whose heart is still beating, the paper notes. It has successfully reversed more than 10,000 lives in the last fifteen years, according to a 2012 report by the U.S. Centers for Disease Control and Prevention.
The widespread painkiller addiction epidemic has fueled the rise of heroin use nationwide, particularly among suburban youth. Between 2007 and 2011, the number of users went from 373,000 to 620,000, according to federal data, and heroin-dependent young adults more than doubled to 109,000 between 2009 and 2011.
Authorities are investigating whether heroin laced with the powerful painkiller fentanyl may have contributed to up to 50 recent fatal overdoses in three states. Fentanyl, an opiate that is 50 to 100 times more potent than heroin, is sometimes added to the street drug to create a stronger high.
According to this article, at least 17 fatal overdoses in Pennsylvania in January were suspected to have been caused by the dangerous blend; while 37 deaths in Maryland since last September and four recent deaths in Flint, Mich. have also been linked to the drug.
A heroin overdose can cause your body to forget to breathe, your blood pressure to dip significantly, and your heart to fail. (Naloxone, otherwise known as Narcan, literally reverses the dangerous effects of taking too much heroin by counteracting the depression of the central nervous system and respiratory system. For every 20% of heroin addicts in a population treated with the drug, about 6.5% of overdose deaths could be prevented, resulting in 2,000 lives saved in a population of 200,000 heroin users, a recent study found.)
Oscar-winning actor Philip Seymour Hoffman died Sunday of an apparent heroin overdose amid a growing problem of addiction and deaths due to the powerful street drug, the Los Angeles Times reports. Many prescription painkiller addicts are turning to heroin to get a similar high after they lose access to popular pills such as OxyContin, the LA Times notes. In 2011, at least 178,000 Americans used heroin for the first time, almost doubling from five years earlier, the Times says, citing the latest available estimate from the Substance Abuse and Mental Health Services Administration.
Hoffman, who was 46, had reportedly been clean for 23 years before falling off the wagon in 2012, according to this article. His death has sparked sympathy from some circles, but as the comments to this article show, there are also many people who remain unsympathetic to drug overdose deaths.
Hoffman’s death follows the opioid-related deaths of other celebrities in recent years, including Heath Ledger and Cory Monteith. It’s not just movie stars who are getting caught up in this trend: poisoning deaths, most of which are due to drugs, have overtaken car accidents as the leading cause of accidental death in the U.S., and responsible for nearly 40,000 fatalities annually. But as Maia Szalavitz notes on Time.com, those numbers don’t have to be so high:
In Wisconsin, where heroin killed nearly 200 people in 2012, legislators are considering legislation that would provide immunity to anyone who helps a person who has overdosed on drugs, and would also provide immunity for possessing and administering the overdose antidote Narcan, according to this article.
They are also considering a separate bill that would target the abuse of opiate painkillers like Vicodin and OxyContin by allowing more medicine collection sites to accept them for disposal. A third measure would create regional treatment centers, the article says.
Heroin overdose deaths surpassed cocaine deaths in Milwaukee County for the first time in 2012, and heroin was present in 32% of fatal overdoses from mixed drug cocktails, according to this article. Narcan is increasingly being used to address the problem: statewide, emergency medical services have seen an increase in naloxone in the last three years, from 2,915 uses in 2010 to 3,247 in 2011 and 3,730 in 2012, the article says.
Overdose hospitalizations accounted for approximately two of every 10,000 hospital visits in 2012, and opiate-related deaths have grown from 2.19 per 100,000 deaths in 2000 to 8.08 in 2011, a report by the State Council on Alcohol and Other Drug Abuse found.